Position:
Clinical Associate Professor
Division:
Neurology
Research Interests:

Current studies aimed at evaluation of protein kinase activity in ALS and other neurodegenerative disorders. Determination of relation between raised cytosolic calcium, protein kinase activation and neuron death.

Education:
M.Sc. Universite de Montreal Sci Neurologiques
MD University of Toronto Medicine
Ph.D. University of London (London, UK) Physiology
Recent Publications:
  • Ajami. B., Bennett, J., Krieger, C., Tetzlaff, W. and Rossi, F.M. (2007) Local self-renewal sustains CNS microglial maintenance and function throughout adult life. Nature, Neuroscience 10(12):1538-43.
  • Petrik, M.S., Wilson, J.M.B, Grant, S.C., Blackband, S.J, Shan, X, Schulz, J.D, Singh, S, Krieger, C. and Shaw, C.A. (2007) Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. Neuromolecular Medicine 9(3):216-29.
  • Cashman N, Tan LY, Krieger C, Mädler B, Mackay A, Mackenzie I, Benny B, Nantel S, Fabros M, Shinobu L, Yousefi M, Eisen A.  Pilot study of granulocyte colony stimulating factor (G-CSF)-mobilized peripheral blood stem cells in amyotrophic lateral sclerosis (ALS).  Muscle Nerve. 2008 May;37(5):620-5.  PMID: 18335482.
  • Parkhouse WS, Cunningham L, McFee I, Miller JM, Whitney D, Pelech SL, Krieger C.  Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis.  Amyotroph Lateral Scler. 2008;9(1):24-34.  PMID: 18273716.
  • Rademakers R, Stewart H, DeJesus-Hernandez M, Krieger C, Graff-Radford n, Fabros M, Briemberg H, Cashman N, Eisen A, Mackenzie I.  FUS gene mutations in familial and sporadic amyotrophic lateral sclerosis.  Muscle Nerve 2010;42(2):170-6.