Position:
Assistant Professor
Division:
Neurology
Research Interests:

My research involved studying a novel extracellular function of the 14-3-3 family of proteins. Although the extracellular form of 14-3-3 proteins were previously detected in the cerebrospinal fluid no specific function was attributed to them until recently. Our group had identified the extracellular 14-3-3 proteins to be a potent MMP-1 inducer in fibroblasts. I studied the MMP-1 inducing effect of lung epithelial cells derived 14-3-3 in initiating events that may lead to airway remodeling in asthma.

Education:
M.D. Shahid Beheshti University; Tehran, Iran
M.S. University of Alberta; Edmonton, Alberta
Recent Publications:
  1. Dowlatshahi D, Butcher K, Asdaghi N, Bernbaum M, Giulivi A, Wasserman J, Poon MC, Coutts S. Poor prognosis in Warfarin-associated Intracranial Hemorrhage despite Anticoagulation Reversal. Stroke, May, 3, 2012.
  2. Asdaghi N, Butcher KS, Hill MD. Risk and Benefits of Thrombolysis in the Elderly. Int J Stroke. 2012 Feb;7(2):142-9.
  3. Asdaghi N, Kilani RT, Hosseini-Tabatabaie A, Odemuyiwa SO, Hackett TL, Knight DA, Ghahary A, Moqbel R. Extracellular 14-3-3 from human lung epithelial cells enhances MMP-1 expression. Molecular and Cellular Biochemistry. 2012 Jan;360(1-2):261-70. Epub 2011 Sep 25.
  4. Asdaghi N, Coutts SB. Imaging Predictors of Outcome in Patients with Transient Ischemic Attack and Minor Stroke. Review of published data from the VISION study. The European Journal of Cardiovascular Medicine, August 2011, Vol I Issue Iv, Issn 2042-4884.
  5. Asdaghi N, Hameed BH, Saini MS, Jeerakathil TJ, Emery D, Butcher KS. Acute perfusion and diffusion abnormalities predict early new MRI lesions after minor stroke and TIA. July 2011, Stroke.
  6. Asdaghi N, Saini M, Hameed B, McCombe JA, Jeerakathil T,Emery D, Butcher KS Oxfordshire Community Stroke Project Classification Poorly Differentiates Small Cortical and Subcortical Infarcts. 2011 Jun, Stroke 2011.
  7. Asdaghi, N, Coutts, SB. Neuroimaging in Stroke. Where does MRI fit in? Nature Review Neurology, 2011 Jan;7(1):6-7.
  8. Tsang. A, Stobbe. RW, Asdaghi. N, Hussain. SH, Bhagat.YA, Beaulieu. C, Emery. E, Butcher. K. Relationship Between Sodium Intensity and Perfusion Deficits in Acute Ischemic Stroke. Journal of Magnetic Resonance Imaging, 2011 Jan;33(1):41-7
  9. Scozzafava J, Jickling G, Asdaghi N, Aladdin Y, Guiliani F. Stuporous Catatonia in Marburg Variant of Multiple Sclerosis. J Clin Neurosci. 2009 Oct;16(10):1328, 1386.
  10. Scozzafava J, Jickling G, Aladdin Y, Asdaghi N, Hussain MS. The Health Benefits of Quitting Smoking, An Opportunity for the Medical Community to Provide Support.  Univ of Alberta Health Sci. J. 2009 Jan; 5 (1).
Awards & Recognition:
  • Health Professional Award Fellowship, Canadian Institute of Health Research (CIHR): Stroke Fellowship Funding, 2009 – 2011