Clinical Assistant Professor
Critical Care Medicine
Chem/Biochem – undergrad University of Toronto
MD University of Toronto
Recent Publications:
  • •Belway D, Henderson W, Keenan SP, Levy A, Dodek PM.  The Effect of Pretransport Stabilization and Specialization of Transport Personnel on Outcome of Critically Ill Patients Transferred Between Hospitals: A Systematic Review of the Literature.  J Crit Care 2006; 21:8-17.
  • •Norena M, Wong H, Thompson WD, Keenan SP, Dodek PM.  Severity of Illness and Comorbidity Scores as Predictors of Intensive Care Outcomes.  J Crit Care 2006; 21:142-150.
  • •The Canadian Critical Care Trials Group.  A randomized trial of diagnostic techniques for ventilator-associated pneumonia.  N Engl J Med 2006;355:2619-2630.
  • •Curtis JR, Cook DJ, Sinuff T, White DB, Hill N, Keenan S, Benditt JO, Kacmarek R, Kirchhoff KT, Levy MM. Noninvasive positive pressure ventilation in critical and palliative care settings: Understanding the goals of therapy.  Critical Care Medicine 2007; 35:932-939.
  • •Keenan SP, Martin CM, Norena M, Wong H, Priestap F, Dodek PM.  Variation in length of ICU stay in patients admitted post-cardiac arrest.  Crit Care Med 2007; 35:836-841.
  • •O’Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk D, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Kaplan A, Keenan S, Lacasse Y, Maltais F, Road J, Rocker G, Sin D, Sinuff T, Voduc N.  Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease – 2007 update. Can Respir J 2007;14(Suppl):5B-32B.
  • •Belway D, Dodek PM, Keenan SP, Norena M, Wong H.  The Role of Transport Intervals in Outcomes for Critically Ill Patients Who Are Transferred to Referral Centers. J Crit Care 2008; 23:287-294.
  • •”Heyland DK, Dodek P, Muscedere J, Day A, Cook D; Canadian Critical Care Trials Group.  Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia.
  • •Crit Care Med. 2008 Mar;36(3):737-44.”
  • •”Meade MO, Cook DJ, Guyatt GH, Slutsky AS, Arabi YM, Cooper DJ, Davies AR, Hand LE, Zhou Q, Thabane L, Austin P, Lapinsky S, Baxter A, Russell J, Skrobik Y, Ronco JJ, Stewart TE; Lung Open Ventilation Study Investigators. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial.
  • •JAMA. 2008 Feb 13;299(6):637-45.”
  • •Muscedere J, Dodek PM, Keenan SP, Fowler R, Cook D, Heyland D for the VAP Guideline Committee and the Canadian Critical Care Trials Group.  Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Prevention  J Crit Care 2008, 23; 126-137.
  • •Muscedere J, Dodek PM, Keenan SP, Fowler R, Cook DJ, Heyland DK for the VAP Guideline Committee and the Canadian Critical Care Trials Group.  Comprehensive Evidence-Based Clinical Practice Guidelines for Ventilator-Associated Pneumonia: Diagnosis and Treatment.  J Crit Care 2008, 23; 138-147.
  • •Russell JA, Walley KR, Singer J, Gordon AC, Hébert PC, Cooper DJ, Holmes CL, Mehta S, Granton JT, Storms MM, Cook DJ, Presneill JJ, Ayers D; VASST Investigators.Vasopressin versus norepinephrine infusion in patients with septic shock.  N Engl J Med. 2008 Feb 28;358(9):877-87.
  • •Sinuff T, Cook DJ, Keenan SP, Adhikari N, Eva K, Mehta S, Burns K, Rocker G, Hill NS. Noninvasive Ventilation for AcuteRespiratory Failure Near the End-of-Life. Crit Care Med 2008; 36:789-794.
  • •Sweet DD, Naismith A, Keenan SP, Sinuff T, Dodek PM.  Missed opportunities for noninvasive positive pressure ventilation: a utilization review.  J Crit Care 2008; 23:111-117.
  • •Azoulay E, Timsit JF, Sprung CL, et al. for the Conflicus Study Investigators.  Prevalence and factors of Intensive Care Unit conflicts: The Conflicus Study.  Am J Respir Crit Care Med 2009;180:853-860.
  • •Burns KEA, Adhikari NKJ, Keenan SP, Meade M.  Noninvasive ventilation to wean critically ill adults from invasive mechanical ventilation:  a meta-analysis update.  BMJ 2009;338:b1574.
  • •Keenan SP, Mehta S.  Noninvasive positive pressure ventilation for patients presenting with acute respiratory failure: the randomized controlled trials.  Resp Care 2009, Jan;54(1):116-26.
  • •Kesecioglu J, Beale R, Stewart TE, et al. for the HL10 INT Study Group.  Exogenous natural surfactant for treatment of acute lung injury and the acute respiratory distress syndrome.  Am J Respir Crit Care Med 2009; 180:989-994.
  • •Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon AF, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet P, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler RA; Canadian Critical Care Trials Group H1N1 Collaborative. Critically ill patients with 2009 Influenza A (H1N1) infection in Canada.  JAMA. 2009 Nov 4;30
  • •Martin CM, Priestap F, Fisher H, Fowler RA, Heyland DK, Keenan SP, Longo C, Morrison T, Bentley D, Antman N.  Outcomes, prevalence and incidence for patients with severe sepsis in a prospective, observational registry: The Canadian Sepsis Treatment and Response (STAR) Registry.  Crit Care Med 2009 Jan;37(1):81-8.
  • •Mehta S, Al-Hashim AK, Keenan SP.  Noninvasive positive pressure ventilation in patients with acute cardiogenic pulmonary edema.  Resp Care 2009, Feb;54(2):186-97.
  • •Burns KE, Meade MO, Lessard MR, Keenan SP, Lellouche F.  Wean Earlier and Automatically with New technology (the WEAN study): a protocol of a multicentre, pilot randomized controlled trial. Trials. 2009 Sep 4;10:81.
  • •Dodek PM, Keenan SP, Norena M, Martin C, Wong H.  Structure, process and outcome of all intensive care units within the province of British Columbia, Canada.  J Intensiv Care 2010, Jan 21, ahead of press, PMID: 20097666.
  • •Dubord J, Dodek PM, Chan K, Keenan SP, Marion S, Wong H.  In-hospital death in critically ill patients who have congestive heart failure: does size of hospital matter?  Am J Med Qual 2010, Feb 9, ahead of press, PMID: 20145195.
  • •Keenan SP. Systematic reviews: summarizing the existing literature.  Intensive Care Med 2010, in press.
  • •Kumar A, Zarychanski R, Light B, Parrillo J, Maki D, Simon D, Laporta D, Lapinsky S, Ellis P, Mirzanejad Y, Martinka G, Keenan S, Wood G, Arabi Y, Feinstein D, Kumar A, Dodek P, Kravetsky L, Doucette S; Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group. Early combination antibiotic therapy yields improved survival compare to monotherapy in septic shock: a propensity anaylsis.  Crit Care Med. 2010 Sep;38(9):1773-85.
  • •Burns KE, Adhikari NK, Keenan SP, Meade MO.  Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with acute respiratory failure. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD004127. Review.
  • •Dodek PM, Norena M, Keenan SP, Teja A, Wong H. Intensive care unit admission for community-acquired pneumonia are seasonal but are not associated with weather or reports of influenza-like illness in the community. J Crit Care. 2010 Oct 29. [Epub ahead of print]PMID: 21036532.
  • •Keenan SP. Noninvasive ventilation in acute lung injury: caution is good, more evidence is better.  Respir Care. 2010 Dec;55(12):1757-9.
  • •Keenan SP, Sinuff T, Burns KE, Muscedere J, Kutsogiannis J, Mehta S, Cook DJ, Ayas N, Adhikari NK, Hand L, Scales DC, Pagnotta R, Lazosky L, Rocker G, Dial S, Laupland K, Sanders K, Dodek P; Canadian Critical Care Trials Group/Canadian Critical Care Society Noninvasive Ventilation Guidelines Group. Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting. CMAJ. 2011 Feb 22;183(3):E195-214. Epub 2011 Feb 14.
  • •Dodek PM, Norena M, Keenan SP, Teja A, Wong H. Intensive care unit admissions for community-acquired pneumonia are seasonal but are not associated with weather or reports of influenza-like illness in the community. J Crit Care. 2011 Jun;26(3):228-33. Epub 2010 Oct 30.