Position:
Honorary Professor
Division:
Respiratory
Research Interests:

There are four areas of research interest: a) asthma & COPD; b) respiratory sleep disorders; c) air pollution and the lungs; d) difficult-to-diagnose pathogens, e.g., viruses.

Education:
MBChB University of Aberdeen, Scotland, UK Bachelor of Medicine and Bachelor of Surgery
MD University of Aberdeen, Scotland, UK Medicine (thesis with commendation)
Recent Publications:
  • Boulet L, Becker A, Bowie D, McIvor A, Hernandez P, Rouleau M, Bourbeau J, Graham I, Legare F, Ward T, Cowie R, Drouin D, Harris SB, Tamblyn R, Ernst P, Tan WC, Partridge M, Godard P, Herrerias C, Wilson J, Stirling L, Rozitis EB, Garvey N, Lougheed D, Labrecque M, Rea R, Holroyde M, Fagnan D, Dorval E, Pogany L, Kaplan A, Cicutto L, Allen M, Mraca S, Fitzgerald M, Borduas F, Logan J.  Implementing Practice Guidelines: A workshop on guidelines dissemination and implementation with a focus on ast
  • Cao Z, Ong KC, Eng P, Tan WC, Ng TP.  Frequent hospital readmissions for acute exacerbation of COPD & their associated factors. Respirology. (2006) Mar;11(2):188-95.
  • Chen YZ, Busse W, Pedersen S, Tan W, Lamm CJ, O’Byrne P. Early Intervention of Recent Onset Mild Persistent Asthma in Children Aged Under 11 Years: the Steroid Treatment As Regular Therapy in Early Asthma (START) Trial. Pediatric Allergy and Immunology  (2006) May;17 Suppl 17:7-13.
  • Leng PH, Mosharraf-Hossain AK, Chan YH, Tan WC. The Clinical Predictors of Hypertension and Sleepiness in an Asian Population with Sleep-disordered Breathing. Ann Academy Med Singapore. (2006) Jan;35(1):6-5.
  • P.O’Byrne, S.Pedersen , W.Busse , W.Tan , Y-Z.Chen , S.Ohlsson , A.Ullman , C.Lamm and R.Pauwels . The effects of early intervention with budesonide on lung function in mild persistent asthma: results from the START study. . CHEST (2006) 129(6):1478-1485.
  • A Sonia Buist, Mary Ann McBurnie, William M Vollmer, Suzanne Gillespie, Peter Burney, David M Mannino, on behalf of the BOLD Collaborative Research Group* International variation in the prevalence of COPD(The BOLD Study): a population-based prevalence study. Lancet 2007; 370: 741-50. [* Site Investigators listed under this collective group].
  • James C. Hogg, Fanny S. F. Chu, Wan C. Tan, Don D. Sin, Sanjay A. Patel, Peter D. Pare1, Fernando J. Martinez, Robert M. Rogers, Barry J. Make, Gerard J. Criner, Reuben M. Cherniack, Amir Sharafkhaneh, James D. Luketich, Harvey O. Coxson1, W. Mark Elliott1, and Frank C. Sciurba. Survival after Lung Volume Reduction in Chronic Obstructive Pulmonary Disease. Insights from Small Airway Pathology. Am J Respir Crit Care Med 2007; 176: 454-459.
  • Ng TP, Niti M, Tan WC, Cao Z, Ong KC, Eng P. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med. 2007 Jan 8;167(1):60-7.
  • Ong BH, Gao Q, Phoon MC, Chow VT, Tan WC, Van Bever HP. Identification of human metapneumovirus and Chlamydophila pneumoniae; in children with asthma and wheeze in Singapore. Singapore Med J. 2007 Apr; 48(4):291-3.
  • Sin, D.D. and W.C. Tan “Breaking Down the “Great Wall” of COPD Care in China” . Am J Respir Crit Care Med 2007; 176(8): 732-3.
  • Wan C Tan, Don Sin, Doug Balson, M Fitzgerald, W Vollmer, S Buist. The Burden of Obstructive Lung Disease [BOLD] study in Vancouver, Canada- Sampling and Recruitment. Canadian Respiratory Journal 2007; 14Suppl A:7A-9A.
  • Wan C. Tan. Insights into Early Treatment of Mild Asthma. Do Inhaled Corticosteroids Make a Difference? Pediatr Drugs 2007; 9 (4): 219-226.
  • Zhang W, Zhang X, Qiu D, Sandford A, Tan WC. IL-4 receptor genetic polymorphisms and asthma in Asian populations. Respir Med. 2007;101(1):186-90. [epub 2006 Jun 6].
  • Busse WW, Pedersen S, Pauwels RA, Tan WC, Chen YZ, Lamm CJ, O’Byrne PM; START Investigators Group The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: effectiveness of early intervention with budesonide in mild persistent asthma. J Allergy Clin Immunol. 2008 May;121(5):1167-74.
  • Wan C Tan, Tze P Ng. Chronic Obstructive Pulmonary Disease in Asia- where East Meets West. CHEST 2008, 133; :517-527.
  • Wan C Tan. Asthma Management in the developing World- Achievements and Challenges. Expert Rev. Resp. Med. 2008; 2(3): 323-328.
  • Ng TP, Niti M, Fones C, Yap KB, Tan WC. Co-morbid association of depression and COPD: a population-based study. Respir Med. 2009 Jun;103(6):895-901. Epub 2009 Jan 10. PubMed PMID: 19136238.
  • O’Byrne PM, Lamm CJ, Busse WW, Tan WC, Pedersen S. The Effects of Inhaled Budesonide on Lung Function in Smokers and Nonsmokers With Mild Persistent Asthma. Chest. 2009 Dec, 136(6):1514-20. [Epub 2009 Aug 26] PubMed PMID: 19710291.
  • O’Byrne PM, Pedersen S, Lamm CJ, Tan WC, Busse WW; START Investigators Group. Severe exacerbations and decline in lung function in asthma. Am J Respir Crit Care Med. 2009 Jan 1;179(1):19-24. Epub 2008 Oct 31. PubMed PMID: 18990678.
  • Tan WC, Lo C, Jong A, Xing L, Fitzgerald MJ, Vollmer WM, Buist SA, Sin DD. Vancouver Burden of Obstructive Lung Disease (BOLD) Research Group. Marijuana and chronic obstructive lung disease: a population-based study. CMAJ. 2009 Apr 14;180(8):814-20. PubMed PMID: 19364790; PubMed Central PMCID: PMC2665947.
  • Tan WC, Seale P, Ip M, Shim YS, Chiang CH, Ng TP, Abisheganadan J, Charoenratanakul S, DeGuia T, Mahayiddin A, Mangunnegoro H, Xu YJ, Zhong NS. Trends in COPD mortality and hospitalizations in countries and regions of Asia-Pacific. Respirology: 2009 Jan;14(1):90-7. PubMed PMID: 19144054.
  • Sadatsafavi M, Lynd L, Marra C, Carleton B, Tan WC, Sullivan S, Fitzgerald M. Direct health care costDirect health care costs associated with asthma in British Columbia. Can Respir J. 2010 March/April;17(2):74-80, PMID: 20422063.
  • Hill K, Goldstein RS, Guyatt GH, Blouin M, Tan WC, Davis LL, Heels-Ansdell DM, Erak M, Bragaglia PJ, Tamari IE, Hodder R, Stanbrook MB. Prevalence and underdiagnosis of chronic obstructive pulmonary disease among patients at risk in primary care CMAJ. 2010 Apr 20;182(7):673-8. Epub 2010 Apr 6.
  • Hackett TL, Scarci M, Zheng L, Tan W, Treasure T, Warner JA. Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease. Respir Res 2010: 11(1): 180. Epub 2010/12/24. DOI:1465-9921-11-180 [pii] 10.1186/1465-9921-11-180.
  • Tan WC. Trends in chronic obstructive pulmonary disease in the Asia-Pacific regions. Curr Opin Pulm Med 2011; 17(2):56-61. Epub 2010/12/24.