Recent Publications

• Al-Alawi A, Mulgrew A, Tench E, Ryan CF.  Prevalence, risk factors and impact on daytime sleepiness and hypertension of periodic leg movements with arousals in patients with obstructive sleep apnea.  J clin Sleep Med In Press 2006.
• Al-Alawi A, Mulgrew A, Tench E, Ryan CF. Prevalence, risk factors and impact on daytime sleepiness and hypertension of periodic limb movement disorder in patients with obstructive sleep apnea. J Clin Sleep Med 2006;2:281-287.
• Al-Alawi A, Ryan CF. Aspergillus pseudomembranous tracheobronchitis complicating treatment of COPD exacerbations. Kuwait Med J  In Press 2006.
• Ayas NT, FitzGerald JM, Fleetham JA, White DP, Schulzer M, Ryan CF, Chaeli R, Mercer GW, Cooper P, Marra CA.  Cost-effectiveness of CPAP therapy for moderate to severe obstructive sleep apneaHypopnea.  Arch Intern Med In Press 2006.
• De Almeida FR, Ayas NT, Otsuka R, Hamilton P, Ryan CF, Lowe AA. Nasal pressure recordings to detect obstructive sleep apnea. Sleep Breath, In Press, 2006.
• Mulgrew AT, Cheema R, Fleetham J, Ryan C. F, Ayas NT. Efficacy and patient satisfaction with auto-adjusting CPAP with variable expiratory pressure versus standard CPAP: A two-night randomized crossover trial. Sleep Breath in Press 2006.
• Otsuka R, de Almieda FR, Lowe AA, Linden W, Ryan F.  The effect of oral appliance therapy on blood pressure in patients with obstructive sleep apnea. Sleep and Breathing In Press 2006.
• Otsuka R, de Almieda FR, Lowe AA, Ryan CF.  A comparison of responders and non-responders to oral appliance therapy used for the treatment of obstructive sleep apnea.  Am J Orthod Dentofacial Orthop 129:2292-9, 2006.
• Alajmi M, Mulgrew AT, Fox J, Davidson W, Schulzer M, Mak E, Ryan, CF, J Fleetham, Ayas NT  Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea-hypopnea: A meta-analysis of randomized controlled trials.  Lung 2007 Mar-Apr;185(2):67-72. Epub 2007 Mar 28.
• Mulgrew A, Fox N, Ayas N, Ryan CF. An algorithm for diagnosis and initial management of obstructive sleep apnea without polysomnography: a validation study. Ann Intern Med In Print February 2007.
• Alajmi M, Mulgrew AT, Fox J, Davidson W, Schulzer M, Mak E, Ryan, CF, J Fleetham, Ayas NT  The impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea-hypopnea: A meta-analysis of randomized controlled trials. Lung In Press 2008.
• Comondore VR, Cheema R, Fox J Butt A, Mancini JGB, Fleetham JA, Ryan CF, Chan S, Ayas NT. The impact of CPAP on cardiovascular biomarkers in minimally symptomatic patients with obstructive sleep apnea: a pilot feasibility randomized crossover trial. Lung 2008 Sept 16 (Epub ahead of print).
• Froese CL, Butt A, Mulgrew A, Cheema R, Speirs MA, Gosnell C, Fleming J, Fleetham J, Ryan CF, Ayas NT. Depression and sleep-related symptoms in an adult first nations population. J Clin Sleep Med 2008;4:356-61.
• Hamer OW, Flint J, Ryan CF, Manos D, Muller NL. Mucoid impaction secondary to mucin-producing metastatic adenocarcinoma of the cervix.Br J Radiol. 2008 Aug;81:e201-3.
• Mulgrew AT, Nasvadi G, Butt A, Cheema R, Fox N, Fleetham JA, Ryan CF, Cooper P, Ayas N. Risk and severity of motor vehicle crashes in patients with obstructive sleep apnoea/hypopnoea. Thorax. 2008 Jun;63:536-41. Epub 2008 Jan 30.
• Tan MCY, Ayas NT, Mulgrew A, Cortes L, FitzGerald JM, Fleetham JA, Schulzer M, Ryan CF, Ghaeli R, Cooper P, Marra CA. Cost-effectiveness of continuous positive airway pressure therapy in patients with obstructive sleep apnea-hypopnea in British Columbia CRJ 2008;15:159-165.
• Comondore VR, Cheema R, Fox J Butt A, Mancini JGB, Fleetham JA, Ryan CF, Chan S, Ayas NT. The impact of CPAP on cardiovascular biomarkers in minimally symptomatic patients with obstructive sleep apnea: a pilot easibility randomized crossover trial.  Lung 2009;187:17-22. Epub 2008 Sep 16.
• Ayas N, Fox J, Epstein L. Ryan CF, Fleetham J. Initial use of portable monitoring versus polysomnography to confirm obstructive sleep apnea in symptomatic patients:an economic decision model. Sleep Medicine 2010;11:320-324.
• Mulgrew AT, Al Lawati N, Ayas NT, Fox N, Hamilton P, Cortes L, Ryan CF. Residual sleep apnea on polysomnography after 3 months of CPAP therapy: clinical implications, predictors and patterns. Sleep Medicine 2010;11:119-125.
• Ayas N, Hirsch-Allen AJ, Goodfellow E, Wenner J, Fleetham J, Ryan F, Kwiatkowska M. The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial. Sleep. Accepted 2011.
• Canadian Sleep Society members: Dales R, Driver H, Dumov I, Fleming J, Fraser K, George C, Khullar A, Mink J, Moffat M, Sullivan GE: Canadian Thoracic Society Committee members: Fleetham JA, Ayas N, Bradley TD, Fitzpatrick M, Kimoff J, Morrison D, Ryan F, Skomro R, Series F, Tsai W. Canadian Sleep Society/Canadian Thoracic Society position paper on the use of portable monitoring for the diagnosis of obstructive sleep apnea/hypopnea in adults. Can Respir J 2011;17:229-232.
• Fleetham J, Ayas N, Bradley D, Fitzpatrick M, Oliver TK, Morrison D, Ryan F, Series F,Skomro R, Tsai W. The Canadian Thoracic Society Sleep Disordered Breathing Committee. Canadian Thoracic Society 2011 guideline update:diagnosis and treatment of sleep disordered breathing. Can Respir J 2011;18:25-47.
• Ryan F. Ambulatory monitoring for obstructive sleep apnea: it’s not the device that matters, but how the data are used. Can Respir J 2011;18:318-319.