Nadia Khan

Professor, General Internal Medicine | MD, MSc

Nadia-Khan-001Dr. Khan is a clinician researcher and general internist at St. Paul’s Hospital and scientific member of the Center for Health Evaluation and Outcomes Sciences (CHEOS). Her central motivation is aimed at providing acute and chronic disease management for vulnerable populations. Through these activities she is member of a number of research teams including the Ethnicity Optimal Health Outcomes (ETHOS) team, an Executive Board Member of Hypertension Canada and sits on the scientific advisory board for the South Asian Health Institute.

Having completed a medical degree at the University of Alberta with Honors in research, Dr. Khan completed a general internal medicine fellowship at the University of Calgary, followed by a MSc in Community Health Sciences (Epidemiology) at the University of Calgary where she was fortunate to be mentored by one of Canada’s leading researchers, Dr. William Ghali. This strong foundation has helped Dr. Khan build her research career, with over 100 publications her work has recently been featured in the Vancouver Sun, OMNI television, and Editor’s choice for BMJ Heart in 2012. She is currently leading in a multinational ethnicity acute coronary syndrome study recruiting almost 2000 patients in Canada, China and India.

“My research area is in understanding how ethnicity and sex impact cardiovascular disease, cardiac risk factors and cardiovascular disease management. I received a MSFHR Career Scientist award to investigate ethnicity and chronic cardiovascular disease management barriers and solutions.”

Over the past 7 years she has systematically investigated cardiovascular disease burden, acute care delivery for ACS, stroke and chronic cardiovascular disease management using multi-provincial population based datasets. This work was supported by four CIHR/HSFC operating grants and a CIHR New Investigator award. Her overall findings have demonstrated that South Asian and Chinese are disproportionately affected by cardiovascular disease and the lifetime health burden will be greater for these populations as they have longer to live with the disease. Working with the ETHOS team, she is now systematically investigating how ethnicity impacts chronic cardiovascular disease using a multicenter cohort study of South Asian, Chinese and White patients with acute coronary syndrome. This research aims to identify specific gaps in chronic cardiovascular care and patient level barriers in these ethnic groups that are not currently known. She was recently awarded a CIHR grant for a randomized controlled trial determining the efficacy of a culturally adapted diabetes management intervention compared with usual care on diabetes and blood pressure outcomes. The long-term goal is to use this new information to inform culturally sensitive interventions to close these care gaps and improve risk factor and cardiovascular disease management of Canada’s largest ethnic populations

When asked how being a member of the Department of Medicine and UBC have helped her achieve her research goals Dr. Khan stressed the importance of the research environment, with access to a large and diverse ethnic population, diversity of the department, and association with a strong outcomes research group (CHEOS), have all been integral to her success.

“Within the Department of Medicine, we are able to foster unique collaborations across disciplines given that the DoM is large and diverse as well. The DoM has provided me continued support since I joined UBC that has given me the opportunity to pursue these important research questions. As a physician, this has been critical to allow me to protect my time as there are few clinician researchers in Canada.”