Assistant Professor
Centre for Heart Lung Innovation, St. Paul’s Hospital
Room 166, 1081 Burrard Street
Vancouver, BC
Research Interests:

Biomarker discovery, biostatistics, cystic fibrosis, epidemiology, exercise physiology, health outcomes, quality improvement, quality of life.

Research Summary:

Dr. Quon is an Adult Respirologist and Clinician-Scientist with a primary clinical and research interest in cystic fibrosis (CF). His research focuses on bridging discoveries in the basic laboratory into the clinic to improve patient outcomes. He is currently searching for novel biomarkers of inflammation and infection to improve disease monitoring in CF. He is Co-Investigator of an international collaboration examining health outcomes for individuals with CF living in Canada and the United States. He is also actively involved in several quality improvement initiatives within the St. Paul’s Hospital Adult CF clinic and several clinical trials investigating new therapies in CF.

University of British Columbia, BSc, Microbiology & Immunology
McGIll University, MD
McGill University, MBA, Healthcare Management
University of Washington, MSc, Epidemiology
UBC James Hogg Research Centre, Centre for Heart and Lung Innovation, Principal Investigator
Recent Publications:

1: Heirali AA, Acosta N, Storey DG, Workentine ML, Somayaji R, Laforest-Lapointe
I, Leung W, Quon BS, Berthiaume Y, Rabin HR, Waddell BJ, Rossi L, Surette MG,
Parkins MD. The effects of cycled inhaled aztreonam on the cystic fibrosis (CF)
lung microbiome. J Cyst Fibros. 2019 Mar 8. pii: S1569-1993(19)30028-1. doi:
10.1016/j.jcf.2019.02.010. [Epub ahead of print] PubMed PMID: 30857926.

2: Desai S, Wong H, Sykes J, Stephenson AL, Singer J, Quon BS. Reply: Predictors
of Reduced Survival for Adult-diagnosed Cystic Fibrosis: Older Age at Diagnosis,
a Substitute for Older Age? Ann Am Thorac Soc. 2019 Jan 30. doi:
10.1513/AnnalsATS.201901-063LE. [Epub ahead of print] PubMed PMID: 30698985.

3: Desai S, Wong H, Sykes J, Stephenson AL, Singer J, Quon BS. Clinical
Characteristics and Predictors of Reduced Survival for Adult-diagnosed Cystic
Fibrosis. Analysis of the Canadian CF Registry. Ann Am Thorac Soc. 2018
Oct;15(10):1177-1185. doi: 10.1513/AnnalsATS.201801-037OC. PubMed PMID: 29944384.

4: Skolnik K, Quon BS. Recent advances in the understanding and management of
cystic fibrosis pulmonary exacerbations. F1000Res. 2018 May 14;7. pii: F1000
Faculty Rev-575. doi: 10.12688/f1000research.13926.1. eCollection 2018. Review.
PubMed PMID: 29862015; PubMed Central PMCID: PMC5954331.

5: Rayment JH, Quon BS. Back to the source – Modern insights into pulmonary
exacerbations and lung function decline from CF registry data. J Cyst Fibros.
2018 Jul;17(4):425-427. doi: 10.1016/j.jcf.2018.05.001. Epub 2018 May 30. PubMed
PMID: 29859835.

6: Saavedra MT, Quon BS, Faino A, Caceres SM, Poch KR, Sanders LA, Malcolm KC,
Nichols DP, Sagel SD, Taylor-Cousar JL, Leach SM, Strand M, Nick JA. Whole Blood
Gene Expression Profiling Predicts Severe Morbidity and Mortality in Cystic
Fibrosis: A 5-Year Follow-Up Study. Ann Am Thorac Soc. 2018 May;15(5):589-598.
doi: 10.1513/AnnalsATS.201707-527OC. PubMed PMID: 29425066.

7: Quon BS, Sykes J, Stanojevic S, Marshall BC, Petren K, Ostrenga J, Fink A,
Elbert A, Faro A, Goss CH, Stephenson AL. Clinical characteristics of cystic
fibrosis patients prior to lung transplantation: An international comparison
between Canada and the United States. Clin Transplant. 2018 Mar;32(3):e13188.
doi: 10.1111/ctr.13188. Epub 2018 Feb 11. PubMed PMID: 29292522; PubMed Central
PMCID: PMC6120341.

8: Roberts JM, Dai DLY, Hollander Z, Ng RT, Tebbutt SJ, Wilcox PG, Sin DD, Quon
BS. Multiple reaction monitoring mass spectrometry to identify novel plasma
protein biomarkers of treatment response in cystic fibrosis pulmonary
exacerbations. J Cyst Fibros. 2018 May;17(3):333-340. doi:
10.1016/j.jcf.2017.10.013. Epub 2017 Nov 22. PubMed PMID: 29174082.

9: Goss CH, Sykes J, Stanojevic S, Marshall B, Petren K, Ostrenga J, Fink A,
Elbert A, Quon BS, Stephenson AL. Comparison of Nutrition and Lung Function
Outcomes in Patients with Cystic Fibrosis Living in Canada and the United States.
Am J Respir Crit Care Med. 2018 Mar 15;197(6):768-775. doi:
10.1164/rccm.201707-1541OC. PubMed PMID: 29099606; PubMed Central PMCID:

10: Lin AH, Kendrick JG, Wilcox PG, Quon BS. Patient knowledge and pulmonary
medication adherence in adult patients with cystic fibrosis. Patient Prefer
Adherence. 2017 Mar 30;11:691-698. doi: 10.2147/PPA.S129088. eCollection 2017.
PubMed PMID: 28408806; PubMed Central PMCID: PMC5383089.

11: Stephenson AL, Sykes J, Stanojevic S, Quon BS, Marshall BC, Petren K,
Ostrenga J, Fink AK, Elbert A, Goss CH. Survival Comparison of Patients With
Cystic Fibrosis in Canada and the United States: A Population-Based Cohort Study.
Ann Intern Med. 2017 Apr 18;166(8):537-546. doi: 10.7326/M16-0858. Epub 2017 Mar
14. PubMed PMID: 28288488; PubMed Central PMCID: PMC5467971.

12: Sharma A, Kirkpatrick G, Chen V, Skolnik K, Hollander Z, Wilcox P, Quon BS.
Clinical utility of C-reactive protein to predict treatment response during
cystic fibrosis pulmonary exacerbations. PLoS One. 2017 Feb 8;12(2):e0171229.
doi: 10.1371/journal.pone.0171229. eCollection 2017. PubMed PMID: 28178305;
PubMed Central PMCID: PMC5298271.

13: Ramos KJ, Quon BS, Heltshe SL, Mayer-Hamblett N, Lease ED, Aitken ML, Weiss
NS, Goss CH. Heterogeneity in Survival in Adult Patients With Cystic Fibrosis
With FEV(1) < 30% of Predicted in the United States. Chest. 2017
Jun;151(6):1320-1328. doi: 10.1016/j.chest.2017.01.019. Epub 2017 Jan 20. PubMed
PMID: 28115168; PubMed Central PMCID: PMC5472512.

14: Skolnik K, Kirkpatrick G, Quon BS. Nontuberculous Mycobacteria in Cystic
Fibrosis. Curr Treat Options Infect Dis. 2016;8(4):259-274. doi:
10.1007/s40506-016-0092-6. Epub 2016 Oct 22. Review. PubMed PMID: 28035194;
PubMed Central PMCID: PMC5155018.

15: Skolnik K, Levy RD, Wilcox PG, Quon BS. Coronary artery disease in cystic
fibrosis: An emerging concern? J Cyst Fibros. 2016 Nov;15(6):e70-e71. doi:
10.1016/j.jcf.2016.09.010. Epub 2016 Oct 14. PubMed PMID: 27751792.

16: Roberts JM, Wilcox PG, Quon BS. Evaluating Adult Cystic Fibrosis Care in BC:
Disparities in Access to a Multidisciplinary Treatment Centre. Can Respir J.
2016;2016:8901756. doi: 10.1155/2016/8901756. Epub 2016 Feb 29. PubMed PMID:
27445568; PubMed Central PMCID: PMC4904545.

17: Quon BS, Wilkie SS, Ramsook AH, Schaeffer MR, Puyat JH, Wilcox PG, Guenette
JA. Qualitative dimensions of exertional dyspnea in adults with cystic fibrosis.
J Appl Physiol (1985). 2016 Aug 1;121(2):449-56. doi:
10.1152/japplphysiol.00391.2016. Epub 2016 Jun 16. PubMed PMID: 27311438.

18: Kew KM, Quinn M, Quon BS, Ducharme FM. Increased versus stable doses of
inhaled corticosteroids for exacerbations of chronic asthma in adults and
children. Cochrane Database Syst Rev. 2016 Jun 7;(6):CD007524. doi:
10.1002/14651858.CD007524.pub4. Review. PubMed PMID: 27272563.

19: Quon BS, Rowe SM. New and emerging targeted therapies for cystic fibrosis.
BMJ. 2016 Mar 30;352:i859. doi: 10.1136/bmj.i859. Review. PubMed PMID: 27030675;
PubMed Central PMCID: PMC4817245.

20: Ramos KJ, Quon BS, Psoter KJ, Lease ED, Mayer-Hamblett N, Aitken ML, Goss CH.
Predictors of non-referral of patients with cystic fibrosis for lung transplant
evaluation in the United States. J Cyst Fibros. 2016 Mar;15(2):196-203. doi:
10.1016/j.jcf.2015.11.005. Epub 2015 Dec 17. PubMed PMID: 26704622; PubMed
Central PMCID: PMC4828327.

21: Roberts JM, Wilcox PG, Quon BS. Evaluating adult cystic fibrosis care in
British Columbia: Disparities in access to a multidisciplinary treatment centre.
Can Respir J. 2015 Nov 3. pii: 17234. [Epub ahead of print] PubMed PMID:

22: Sykes J, Stanojevic S, Goss CH, Quon BS, Marshall BC, Petren K, Ostrenga J,
Fink A, Elbert A, Stephenson AL. A standardized approach to estimating survival
statistics for population-based cystic fibrosis registry cohorts. J Clin
Epidemiol. 2016 Feb;70:206-13. doi: 10.1016/j.jclinepi.2015.08.026. Epub 2015 Oct
3. PubMed PMID: 26434789; PubMed Central PMCID: PMC4889445.

23: Quon BS, Wilkie SS, Molgat-Seon Y, Schaeffer MR, Ramsook AH, Wilcox PG,
Guenette JA. Cardiorespiratory and sensory responses to exercise in adults with
mild cystic fibrosis. J Appl Physiol (1985). 2015 Dec 1;119(11):1289-96. doi:
10.1152/japplphysiol.00692.2015. Epub 2015 Oct 1. PubMed PMID: 26429870; PubMed
Central PMCID: PMC4669346.

24: Vanden Driessche K, Hens N, Tilley P, Quon BS, Chilvers MA, de Groot R,
Cotton MF, Marais BJ, Speert DP, Zlosnik JE. Surgical masks reduce airborne
spread of Pseudomonas aeruginosa in colonized patients with cystic fibrosis. Am J
Respir Crit Care Med. 2015 Oct 1;192(7):897-9. doi: 10.1164/rccm.201503-0481LE.
PubMed PMID: 26426786.

25: Habib AR, Quon BS, Buxton JA, Alsaleh S, Singer J, Manji J, Wicox PG, Javer
AR. The Sino-Nasal Outcome Test-22 as a tool to identify chronic rhinosinusitis
in adults with cystic fibrosis. Int Forum Allergy Rhinol. 2015 Dec;5(12):1111-7.
doi: 10.1002/alr.21607. Epub 2015 Jul 30. PubMed PMID: 26228968.

26: Quon BS, Wilcox PG. A new era of personalized medicine for cystic fibrosis –
at last! Can Respir J. 2015 Sep-Oct;22(5):257-60. Epub 2015 Jun 17. Review.
PubMed PMID: 26083544; PubMed Central PMCID: PMC4596645.

27: Habib AR, Buxton JA, Singer J, Wilcox PG, Javer AR, Quon BS. Association
between Chronic Rhinosinusitis and Health-Related Quality of Life in Adults with
Cystic Fibrosis. Ann Am Thorac Soc. 2015 Aug;12(8):1163-9. doi:
10.1513/AnnalsATS.201504-191OC. PubMed PMID: 26011015.

28: Quon BS, Dai DL, Hollander Z, Ng RT, Tebbutt SJ, Man SF, Wilcox PG, Sin DD.
Discovery of novel plasma protein biomarkers to predict imminent cystic fibrosis
pulmonary exacerbations using multiple reaction monitoring mass spectrometry.
Thorax. 2016 Mar;71(3):216-22. doi: 10.1136/thoraxjnl-2014-206710. Epub 2015 Mar
16. PubMed PMID: 25777587.

29: Blondon M, Quon BS, Harrington LB, Bounameaux H, Smith NL. Association
between newborn birth weight and the risk of postpartum maternal venous
thromboembolism: a population-based case-control study. Circulation. 2015 Apr
28;131(17):1471-6; discussion 1476. doi: 10.1161/CIRCULATIONAHA.114.012749. Epub
2015 Mar 5. PubMed PMID: 25745022.

30: Habib AR, Manji J, Wilcox PG, Javer AR, Buxton JA, Quon BS. A systematic
review of factors associated with health-related quality of life in adolescents
and adults with cystic fibrosis. Ann Am Thorac Soc. 2015 Mar;12(3):420-8. doi:
10.1513/AnnalsATS.201408-393OC. Review. PubMed PMID: 25642976.

31: Quon BS, Bentham WD, Unutzer J, Chan YF, Goss CH, Aitken ML. Prevalence of
symptoms of depression and anxiety in adults with cystic fibrosis based on the
PHQ-9 and GAD-7 screening questionnaires. Psychosomatics. 2015
Jul-Aug;56(4):345-53. doi: 10.1016/j.psym.2014.05.017. Epub 2014 Jun 2. PubMed
PMID: 25556569.

32: Quon BS, Goss CH. Adult-onset asthma prevention. Should we be investing in
antioxidant defense? Am J Respir Crit Care Med. 2015 Jan 1;191(1):4-5. doi:
10.1164/rccm.201411-2089ED. PubMed PMID: 25551340; PubMed Central PMCID:

33: Quon BS, Schaeffer MR, Molgat-Seon Y, Wilkie SS, Wilcox PG, Guenette JA.
Physiological mechanisms of dyspnea relief following ivacaftor in cystic
fibrosis: a case report. Respir Physiol Neurobiol. 2015 Jan 1;205:105-8. doi:
10.1016/j.resp.2014.10.019. Epub 2014 Nov 5. PubMed PMID: 25447681.

More Publications can be found on PubMed.

Awards & Recognition:
  • Michael Smith Foundation for Health Research Scholar Award (2018 – 2022)
  • Cystic Fibrosis Canada UBC Clinician-Scientist Award (Jan 1, 2014 – Dec 31, 2018)

British Columbia Lung Association Grant-in-Aid (2014 to 2016)

INDE 420 Clinical Skills: History and Physical Exam (Bedside)