Clinical Assistant Professor
General Internal Medicine
St. Paul’s Hospital
5910 – 1081 Burrard Street
Vancouver, British Columbia V6Z 1Y6
Research Interests:

Dr Staples’ research interests include traffic safety, injury prevention, medical risk factors for injury, and unplanned readmissions to hospital. He seeks to use the techniques of clinical epidemiology and British Columbia’s powerful population-based data resources to generate novel insights and improve population health.

Research Summary:

Dr Staples’  highest impact study used 25 years of US national data and found that fatal traffic crashes were 12% higher during the annual “4/20” cannabis celebrations (JAMA Int Med 2018). This work was highlighted in over 125 media publications including TIME, Newsweek, Gizmodo, BBC radio, Freakonomics Twitter, Reuters, and the Associated Press. A related study examining childhood pedestrian fatalities on Halloween (JAMA Pediatrics 2019) was discussed by the New York Times, the Washington Post, U.S. News & World Report, the L.A. Times, The Daily Mail (UK), and The National Post.

His largest study examined 10 years of Ontario’s linked administrative data and identified a cohort of about 200,000 patients to examine mortality after hospital readmission (CMAJ Open 2014). Readmission to a hospital other than the original facility resulted in a 4% absolute increase in 30-day mortality that was not entirely explained by patient or hospital characteristics.

More recent publications have focused on the consequences and prevention of injury. One study compared the risks of American spaceflight to the risks of American road travel, highlighting that conventional population-level measures of traffic safety may inadequately communicate risk (Am J Med 2014). Two subsequent studies used a nationally-representative cohort of trauma patients seen in U.S. emergency departments to evaluate the appropriateness of applying traumatic brain injury prognostic scores to the elderly (J Head Trauma Rehab 2015; Brain Inj 2016). Dr. Staples also co-led a study modeling the effects of a nationally-implemented motorcycle helmet law in Vietnam, finding that such a policy is dominantly cost-effective and averts medical impoverishment (Inj Prev 2016).

His work has been presented at Hospital Medicine 2014 (the largest conference for hospital medicine in the United States), the Society for Advancement of Violence and Injury Research (2015), and the International Health Economics Association (2015) and has been included in the upcoming Disease Control Priorities (3rd edition).

University of Alberta, MD
University of British Columbia, Medical Residency
University of British Columbia, Chief Residency
University of British Columbia, General Internal Medicine Fellowship
Harvard University, Masters of Public Health
Institute for Clinical Evaluative Sciences, New England Journal of Medicine Editorial Fellowship
Institute for Clinical Evaluative Sciences, Health Services Research Fellowship
Recent Publications:

Publications can be reviewed on PubMed (https://www.ncbi.nlm.nih.gov/pubmed/?term=Staples%20JA%5BAuthor%5D&cauthor=true&cauthor_uid=29102452) or Google Scholar (https://scholar.google.ca/citations?hl=en&user=_E6HzZsAAAAJ).

  1. The efficacy and safety of alprazolam versus other benzodiazepines in the treatment of panic disorder
    S Moylan, J Staples, SA Ward, J Rogerson, DJ Stein, M Berk
    Journal of clinical psychopharmacology 31 (5), 647-652- 2011
  2. Injury prevention and environmental health: Key messages from Disease Control Priorities
    CN Mock, R Nugent, O Kobusingye
    Disease Control Priorities (Third edition). Volume 7: Injury prevention and Environmental Health
  3. Helmet regulation in Vietnam: Impact on health, equity, and medical impoverishment
    VS Olson Z*, Staples JA*, Mock C, Nguyen NP, Bachani AM, Nugent R
    Disease Control Priorities (Third edition), Volume 7: Injury Prevention and Environmental Health
  4. Site of hospital readmission and mortality: a population-based retrospective cohort study
    JA Staples, D Thiruchelvam, DA Redelmeier
    CMAJ open 2 (2), E77
  5. The April 20 cannabis celebration and fatal traffic crashes in the United States
    JA Staples, DA Redelmeier
    JAMA Internal Medicine 178 (4), 569-572
  6. The application of IMPACT prognostic models to elderly adults with traumatic brain injury: A population-based observational cohort study
    RFP Staples JA, Wang J, Zaros MC, Jurkovich GJ
    Brain Injury
  7. The application of the CRASH-CT prognostic model for older adults With traumatic brain injury: A population-based observational cohort study
    JA Staples, J Wang, B Mills, N Temkin, MC Zaros, GJ Jurkovich, FP Rivara
    The Journal of head trauma rehabilitation 31 (5), E8-E14
  8. Progressive kidney disease in three sisters with elevated lipoprotein (a)
    J Staples, P Taylor, A Magil, J Frohlich, SM Johnston, M Koschinsky, …
    Nephrology Dialysis Transplantation 23 (5), 1756-1759
  9. Pedestrian fatalities associated with Halloween in the United States
    JA Staples, C Yip, DA Redelmeier
    JAMA pediatrics 173 (1), 101-103
  10. Prospective evaluation of patients referred for obscure bleeding: how many patients actually have small bowel bleeding? Update at one year
    J Staples, M Mcloughlin, P Lakzadeh, I Zandieh, J Al Ali, RA Enns
    Gastrointestinal Endoscopy 67 (5), AB258
  11. Fatality risks on the road and in space
    JA Staples, DA Redelmeier
    The American journal of medicine 127 (6), 467-468. e13
  12. Crashes on cannabis celebration day
    JA Staples, DA Redelmeier
    Injury prevention, injuryprev-2019-043262
  13. Bubble-Wrapping Halloween—Reply
    JA Staples, C Yip, DA Redelmeier
    JAMA pediatrics 173 (5), 495-495
  14. Association Between April 20 Cannabis Celebration and Fatal Crashes
    JA Staples, DA Redelmeier
    JAMA internal medicine 179 (3), 456-456
  15. Preventability of 28-Day Hospital Readmissions in General Internal Medicine Patients: A Retrospective Analysis at a Quaternary Hospital
    C Shuster, A Hurlburt, T Yung, T Wan, JA Staples, P Tam
    Quality Management in Healthcare 27 (3), 151-156
  16. Unplanned hospital readmissions in British Columbia
    C Shuster, A Hurlburt, P Tam, JA Staples
    British Columbia Medical Journal 60 (5), 263 – 267
  17. Halloween and Fatal Pedestrian Crashes in the United States
    C Yip, JA Staples
  18. Syncope and presyncope as a presenting symptom or discharge diagnosis in the emergency department: An administrative data validation study
    JA Staples, C Vadeanu, B Gu, S Erdelyi, H Chan, JR Brubacher
    Canadian Journal of Cardiology 33 (12), 1729-1732
  19. Medical emergencies in medical imaging
    JA Staples, DA Redelmeier
    BMJ Qual Saf 21 (6), 446-447
  20. A new internet-based learning resource for internal medicine residents
    RY Wong, CJ Ryerson, HH Ko, SJ Millington, DJ Renouf, JA Staples
    Canadian Journal of General Internal Medicine 3 (2), 7-7
Awards & Recognition:
  • VCHRI Mentored Clinician Scientist Award (2017)
  • PHCRI/VCHRI Innovation and Translation Award (2017)
  • CIHR Project Scheme Grant (2019)
  • Heart and Stroke Foundation of Canada Grant-in-Aid (2019)
  • CIHR Project Scheme Grant (2016)