Multiple Sclerosis (MS) is a degenerative disease of the brain and spinal cord. Every day, 3 more Canadians are diagnosed with this progressive disorder with no cure. My research goals are to investigate possible underlying factors driving disease progression – from genes to the environment. Whether current MS drugs have any long-term beneficial or even harmful effects will also be examined. A core component of this program will focus on bringing together, for the first time, multiple large health databases created for over two decades by physicians and pharmacists. Ultimately, we aim to improve the health, treatment options and outcome for people with MS.