Position:
Assistant Professor
Medical Director, Interdisciplinary Substance Use Program, Providence Health Care
Head, Interdepartmental Division of Addiction Medicine, St. Paul’s Hospital
Clinician Scientist, British Columbia Centre on Substance Use
Division:
AIDS
Research Interests:

Observational studies and clinical trials, addiction medicine, medical education, addiction and drug policy, harm reduction, opioid agonist treatment

Research Summary:

Dr. Nolan’s research is focused on improving evidence-based treatment for individuals with a substance use disorder. She is the Principal Investigator for a novel hospital-based cohort study that seeks to understand health outcomes for individuals with a substance use disorder during hospitalization and following discharge. Furthermore, Dr. Nolan is interested in ensuring equal access to evidence-based medications for incarcerated individuals and is developing an evaluation strategy for a Correctional Health Services pilot study of Community Transition Teams. Dr. Nolan is also a Co-Principal Investigator on a novel hospital-based opioid stewardship program whose focus is to reduce inappropriate opioid prescribing in the acute care setting, and a Co-Investigator on two randomized controlled trials evaluating the efficacy of two medications for the treatment of opioid use disorder. Dr. Nolan’s work has been recognized as being impactful, resulting in the Vincent P. Dole Award for Research Excellence and a research scholarship from the Research in Addiction Medicine Scholars Program, jointly led by Yale and Boston. Furthermore, she has been recognized for her excellence in clinical teaching and was a recipient of UBC’s 2018 Fay R. Dirks Award for Teaching Excellence.

Education:
Research in Addiction Medicine Scholars Program, Yale and Boston University
International Collaborative Addiction Medicine Research Fellowship, BC Centre on Substance Use
St. Paul’s Goldcorp Addiction Medicine Fellowship Program , dip. ABAM
General Internal Medicine Fellowship, University of British Columbia, FRCPC
Internal Medicine Residency, University of British Columbia, FRCPC
Royal College of Surgeons in Ireland, MD
Affiliations
UBC Department of Medicine, Division of Health Equity
Providence Health Care, Medical Director
Recent Publications:

1. Imtiaz S, Li A, Garg A, Dhanani S, Nolan S. A correlation between annual rates of overdose mortality and deceased organ donation in Canada. Progress in Transplantation. February 26, 2019. (Accepted).
2. Braithwaite V, Nolan S. Hospital-based addiction medicine healthcare providers: high demand, short supply. Journal of Addiction Medicine. Jan 4, 2019. PMID: 30633046.
3. Ti L, Nolan S. Opioid stewardship programs: a systems level intervention to manage acute pain in hospital settings? Response letter to: Herzig SJ. Annals for Hospitalists Inpatient Notes – Managing Acute Pain in the Hospital in the Face of the Opioid Crisis. Annals of Internal Medicine, Jan 2019. (accepted).
4. Nolan S, Socias ME, Wood E. The Threat of an International Opioid Crisis. Current Addiction Reports. Sept 26, 2018.
5. Fairgrieve C, Fairbairn N, Samet JH, Nolan S. Nontraditional Alcohol and Opioid Agonist Treatment Interventions. Med Clin North Am. July 2018, 102(4):683-696. PMID: 29933823.
6. Weinstein Z, Wakeman S, Nolan S. The inpatient addiction consult service – expertise for hospitalized patients with complex addiction problems. Med Clin North Am. July 2018, 102(4):587-601. PMID: 29933817.
7. Nolan S, Buxton J, Dobrer S, Don H, Hayashi K, Milloy MJ, Kerr T, Montaner J, Wood E. Awareness, possession and use of take home naloxone among illicit drug users in a Canadian setting. Public Health Rep. Sept-Oct 2017, 132(5):563-9. PMID: 28750193.
8. Dewar K, Nolan S. Chronic hypertension, recreational cocaine use and a subsequent acute aortic dissection in a young adult. BMJ Case Reports. Oct 27, 2017. PMID: 29079671.
9. Hill M, Vipler S, Sutherland C, Nolan S. Challenges of treatment of acutely ill patients enrolled in a managed alcohol program. Drug Alcohol Rev. 2017. PMID: 28868652.
10. Nolan S, Walley AY, Heeren TC, Patts GC, Ventura AS, Sullivan MM, Samet JH, Saitz R. HIV-infected individuals who use alcohol and other drugs, and a virologic suppression. AIDS Care. Sept 29, 2017, 29(9): 1129 – 36. PMID: 28513200.
11. McIsaac J, Nolan S. Dilated cardiomyopathy in a young man with polysubstance use. CJAM. 2017;8(2):23-25.
12. Zivanovic R, Wood E, Nolan S. Naloxone infusion for an unknown ingestion: a case report. Canadian Journal of Addiction 2017; 7(4): 19-24
13. Nolan S, Klimas J, Wood E. Alcohol use in opioid agonist treatment: A review. Addict Sci Clin Pract Dec 8, 2016; 11(1): 17. PMID: 27931253.
14. Zivanovic R, Wood E, Nolan S. A clinical review of the risk factors, diagnosis, treatment and prevention of opioid related harms. UBCMJ. 2016:7(2): 44-47.
15. Nolan S, Hayashi K, Milloy M-J, Kerr T, Dong H, Lima VD, Lappalainen L, Montaner J, Wood E. The impact of low-threshold methadone maintenance treatment on mortality in a Canadian setting. Drug Alcohol Depend. Nov 1, 2015, 156: 57-61. PMID: 26455554
16. Nolan S, Wood E, Montaner J. Antiretroviral treatment initiation: Author’s reply. Lancet Infect Dis. 2014 Dec;14(12): 1175.
17. Nolan S, Dias Lima V, Fairbairn N, Kerr T, Montaner J, Grebely J, Wood E. The impact of methadone maintenance therapy on hepatitis C incidence among illicit drug users. Addiction. Dec 2014, 109(12): 2053-9. PMID: 25041346.
18. Nolan S, Wood E. Methadone and QTc screening: weighing the risks and benefits. Canadian Journal of Addiction. 2014 Jun; 5(2): 17-9.
19. Nolan S, Wood E. End of the debate about antiretroviral treatment initiation. Lancet Infect Dis. 2014 Apr; 14(4): 258-9.
20. Nolan S, DeBeck K, Nguyen P, Kerr T, Wood E. Binge drug use among street-involved youth in a Canadian setting. Addiction Research & Theory. 2014, 22(6): 535-40. PMID: 26109928.
21. Nolan S, Milloy MJ, Zhang R, Kerr T, Hogg RS, Montaner JS, Wood E. Adherence and plasma HIV RNA response to antiretroviral therapy among HIV-seropositive injection drug users in a Canadian setting. AIDS Care. Aug 2011, 23(8): 980-7. PMID: 21480010.

More Publications are available on PubMed.

Awards & Recognition:
  1. University of British Columbia Department of Medicine Fay R. Dirks Award for Teaching Excellence, 2018
  2. Michael Smith Foundation for Health Research/St. Paul’s Foundation Scholar Award, 2017-2022
  3. St. Paul’s Foundation/Providence Health Care Research Institute Initiative’s Early Career Research Award, 2017
  4. Research in Addiction Medicine Scholars (RAMS) Program, 2013-2015
  5. Vincent Dole Award for Excellence in Research, 2014
  • University of British Columbia – Development of a Transformative Health and Justice Research Cluster
  • Vancouver Foundation – An Evaluation of Safer Opioid Prescribing (AESOP): The AESOP Study
  • Vancouver Foundation – Achieving Resilience, Stability, and Wellbeing through Peer Programs and Harm Reduction: Strength-Based Research with People Who Use Drugs at Overdoes Prevention Society (OPPRA Study)
  • Vancouver Foundation – Substance Use and Addiction Services Engagement Among Vulnerable Youth
  • SickKids Foundation/Canadian Institutes of Health Research (CIHR)-Institute of Human Development and youth health (IHDCYH) – Substance Use and Addiction Services Engagement among Vulnerable Youth: An Ethno-Epidemiological Study
  • CIHR Planning and Dissemination Grant-Institute Community Support – Establishing an Interdisciplinary Research Collaboration to Investigate the Ethical and Social Implications of Artificial Intelligence Interventions on the Health of People Living with Substance Use Disorders
  • CIHR Project Grant – Repurposing slow-release oral morphine as new oral alternative for the treatment of opioid use disorder
  • CIHR Operating Grant – CRISM Implementation Science Program on Opioid Interventions and Services-BC Addiction Network
  • CIHR – Initiation of opioid agonist therapy for daily witnessed methadone or flexible take-home dosing of buprenorphine/naloxone for prescription opioid users: A pragmatic patient centred randomized controlled trial
  • CIHR (Canadian Research Initiative in Substance Misuse-Nodes) – The British Columbia Addiction Network
  • CIHR (Canadian Research Initiative in Substance Misuse) – A prospective cohort of substance users in British Columbia: Tracking health outcomes & health care utilization among patients evaluated for addiction care (The OPAC Study)
  • US National Institutes of Health/National Institute on Drug Abuse – Impacts of universal access to HIV/AIDS care among HIV+injection drug users
  • US National Institutes of Health/National Institute on Drug Abuse – Vancouver Drug Users Study: Evaluating the Natural History of Injection Drug Use
  • US National Institutes of Health/National Institute on Drug Abuse – HIV researchers mentoring the next generation of addiction clinician scientists

Dr. Seonaid Nolan is currently a Research Mentor for the International Collaborative Addiction Medicine Fellowship, and the Boston Research in Addiction Medicine Scholars Program. Dr. Nolan is also a Research Supervisor for first and second year UBC medical students, completing a Flexible and Enhanced Learning (FLEX) research project with the British Columbia on Substance Use. Since 2016, Dr. Nolan has worked with over 15 research trainees on multiple research projects. In addition to these mentoring roles, Dr. Nolan is also the Medical Director, and a physician at North America’s largest Interdisciplinary Substance Use Program at Providence Health Care, where she has trained over 150 medical students, residents and physicians.