Howard Lim

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Vision Statement

Dr.

Howard Lim

Position

Clinical Associate Professor

Division

Medical Oncology

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Overview
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Research Interests

Research Summary

Research Highlights

Personal

Howard Lim is a Medical Oncologist at B.C. Cancer Agency – Vancouver and Clinical Associate Professor in the Faculty of Medicine at University of British Columbia. He Treats Gastrointestinal Cancers. He is also actively involved in clinical trials, ethics and genomic based research.

Education and Affiliations
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Education

Bachelor of Science Department of Biochemistry, University of British Columbia,

Doctor of Medicine University of British Columbia,

Doctor of Philosophy Department of Pathology and Laboratory Medicine, University of British Columbia,

Affiliations

Publications and Awards
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Recent Publications

  • Melosky BL, Lim HJ, Davies JM, Gill S, Kollmannsberger CK, Ho MY, Vandt SA, Renouf DJ. A phase II trial of the effect of perindopril on hand-foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC. Cancer Chemother Pharmacol. 2018 Dec 8. PMID: 30535909
  • Tsang ES, Shen Y, Chooback N, Ho C, Jones M, Renouf DJ, Lim H, Sun S, Yip S, Pleasance E, Ionescu DN, Mungall K, Kasaian K, Ma Y, Zhao Y, Mungall A, Moore R, Jones SJM, Marra M, Laskin J. Clinical Outcomes after Whole Genome Sequencing in Patients with Metastatic Non-Small Cell Lung Cancer. Cold Spring Harb Mol Case Stud. 2018 Dec 4. PMID: 30514790
    Tsang ES, Wong HL, Wang Y, Renouf DJ, Cheung WY, Lim HJ, Gill S, Loree JM, Kennecke HF. Outcomes and Characteristics of Patients Receiving Second-line Therapy for Advanced Pancreatic Cancer. Am J Clin Oncol. 2018 Nov 28. PMID: 30499841
  • Thibodeau ML, Reisle C, Zhao E, Martin LA, Alwelaie Y, Mungall KL, Ch’ng C, Thomas R, Ng T, Yip S, Lim H, Sun S, Young SS, Karsan A, Zhao Y, Mungall AJ, Moore RA, Renouf D, Gelmon K, Ma YP, Hayes M, Laskin J, Marra MA, Schrader KA, Jones SJM. Corrigendum: Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline CHEK2:c.1100delC mutation and a concomitant diagnosis of metastatic invasive ductal breast carcinoma. Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4). PMID: 30068734
  • Thibodeau ML, Bonakdar M, Zhao E, Mungall KL, Reisle C, Zhang W, Bye MH, Thiessen N, Bleile D, Mungall AJ, Ma YP, Jones MR, Renouf DJ, Lim HJ, Yip S, Ng T, Ho C, Laskin J, Marra MA, Schrader KA, Jones SJM. Whole genome and whole transcriptome genomic profiling of a metastatic eccrine porocarcinoma. NPJ Precis Oncol. 2018 Mar 19;2(1):8. PMID: 29872726
  • Samawi HH, Sim HW, Chan KK, Alghamdi MA, Lee-Ying RM, Knox JJ, Gill P, Romagnino A, Batuyong E, Ko YJ, Davies JM, Lim HJ, Cheung WY, Tam VC Prognosis of patients with hepatocellular carcinoma treated with sorafenib: a comparison of five models in a large Canadian database.; CHORD Consortium.Cancer Med. 2018 May 15. PMID: 29766659
  • Jonker DJ, Tang PA, Kennecke H, Welch SA, Cripps MC, Asmis T, Chalchal H, Tomiak A, Lim H, Ko YJ, Chen EX, Alcindor T, Goffin JR, Korpanty GJ, Feilotter H, Tsao MS, Theis A, Tu D, Seymour L. A Randomized Phase II Study of FOLFOX6/Bevacizumab With or Without Pelareorep in Patients With Metastatic Colorectal Cancer: IND.210, a Canadian Cancer Trials Group Trial. Clin Colorectal Cancer. 2018 Sep;17(3):231-239.e7. PMID: 29653857
  • Chahal M, Pleasance E, Grewal J, Zhao E, Ng T, Chapman E, Jones MR, Shen Y, Mungall KL, Bonakdar M, Taylor GA, Ma Y, Mungall AJ, Moore RA, Lim H, Renouf D, Yip S, Jones SJM, Marra MA, Laskin J. Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making. Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). PMID: 29610392
  • Owen DR, Wong HL, Bonakdar M, Jones M, Hughes CS, Morin GB, Jones SJM, Renouf DJ, Lim H, Laskin J, Marra M, Yip S, Schaeffer DF. Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases. Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). PMID: 29438965
  • Zhao EY, Shen Y, Pleasance E, Kasaian K, Leelakumari S, Jones M, Bose P, Ch’ng C, Reisle C, Eirew P, Corbett R, Mungall KL, Thiessen N, Ma Y, Schein JE, Mungall AJ, Zhao Y, Moore RA, Den Brok W, Wilson S, Villa D, Shenkier T, Lohrisch C, Chia S, Yip S, Gelmon K, Lim H, Renouf D, Sun S, Schrader KA, Young S, Bosdet I, Karsan A, Laskin J, Marra MA, Jones SJM. Homologous Recombination Deficiency and Platinum-Based Therapy Outcomes in Advanced Breast Cancer. Clin Cancer Res. 2017 Dec 15;23(24):7521-7530. PMID: 29246904
  • McKenzie MR, Hawley P, Barwich D, Lim HJ. In Response to “Medical Assistance in Dying in Canada”.J Oncol Pract. 2018 Jan;14(1):56-57. PMID: 29144863
  • Wong HL, Yang KC, Shen Y, Zhao EY, Loree JM, Kennecke HF, Kalloger SE, Karasinska JM, Lim HJ, Mungall AJ, Feng X, Davies JM, Schrader K, Zhou C, Karsan A, Jones SJM, Laskin J, Marra MA, Schaeffer DF, Gorski SM, Renouf DJ. Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing. Cold Spring Harb Mol Case Stud. 2018 Feb 1;4(1). PMID: 29092957 Free PMC Article
  • Primary Care Versus Oncology-Based Surveillance Following Adjuvant Chemotherapy in Resected Pancreatic Cancer. Samawi HH, Yin Y, Lim HJ, Cheung WY. J Gastrointest Cancer. 2018 Dec;49(4):429-436. doi: 10.1007/s12029-017-9988-8. PMID: 28674913
  • A Comparison of Survival by Site of Metastatic Resection in Metastatic Colorectal Cancer. Lee-Ying R, Bernard B, Gresham G, Chen L, Speers C, Kennecke HF, Lim HJ, Cheung WY, Renouf DJ Clin Colorectal Cancer. 2017 Jun;16(2):e23-e28. doi: 10.1016/j.clcc.2016.07.018. Epub 2016 Aug 9.PMID: 27637559.
  • Lim, H.J. and Kennecke, H.: Landmarks Commentary: Pancreatic Cancer Oncology Exchange. 7(3):14-15, August 2008.
  • Lim H.J. and Gill, S.: Landmarks Commentary: KRAS as a Predictive Marker in Metastatic Colorectal Cancer Oncology Exchange 7(4)9-12, November 2008.
  • Lim HJ and Shah A. Fifty years of 5-flurouracil. (Review) Oncology Exchange. 6:30-35, August 2007.

Awards & Recognition

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